Dados do Trabalho

Título

Mortality rate of myelodysplasia syndrome in brazil

Introdução

Myelodysplastic Syndromes (MDSs) are clonal hematological alterations that present cytopenias of one or more hematopoietic lineages. Your etiology is divided into primary and secondary, with the primary coming from genetic alterations and the secondary coming from exposure to toxic factors, such as chemotherapy, radiotherapy and chemical substances used in industry and agriculture. MDS has a clinical picture originating from the medullary and generated cytopenias, presenting anemia due to the reduction of red blood cells, cutaneous-mucous bleeding caused by thrombocytopenia and/or recurrent due to neutropenia. Furthermore, in several countries, including Brazil, an increase in the incidence of MDS with increasing age has been observed, being associated with increased life expectancy and better diagnostic methods.

Objetivo

The aim of this work is to analyze the epidemiological profile of mortality due to Myelodysplastic Syndromes in Brazil.

Casuística

This is a descriptive cross-sectional study with secondary data from the national database, DATASUS.

Método

For the analysis, data were collected from the years 2015 to 2020, with stratification by age group, gender and color/race. Subsequently, they were cross-referenced with population estimates to calculate mortality rates.

Resultados

In the period observed, there were an average of 5,710 deaths, the incidence of mortality was prevalent in the age group greater than or equal to 80 years, with the second prevalence being the age group from 70 to 79 years. There is a progressive increase in the incidence of mortality with increasing age, with a prevalence of 0.85% in the young population (20-29 years) and in the adult population (40-49 years) of 2.83%. When analyzing the predominance between genders, males present more deaths than females, around 5% higher. When comparing mortalities by color/race, the white race has a higher preponderance of deaths, with about 68%, followed by the brown race with approximately 23% and presenting the lowest rate, 0.17%, the indigenous race.

Discussão e conclusões

Therefore, in view of what was highlighted, one can contemplate the main factors that condition a higher mortality resulting from MDS. Thus, it is essential to develop public policies aimed at health promotion and prevention aimed at this pathology, leading to a better quality of life.

Área

Hematologia